Reactome | p-Y393-ABL1 phosphorylates tyrosine-407 of YAP1

Schema > Reaction > Entries

p-Y393-ABL1 phosphorylates tyrosine-407 of YAP1 Show undefined attributes

catalystActivity	[CatalystActivity:10908485] protein tyrosine kinase activity of p-Y393-ABL1 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10908487
displayName	p-Y393-ABL1 phosphorylates tyrosine-407 of YAP1
eventOf	[Pathway:R-DME-9860927] Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-DME-9865176] p-Y407-YAP1 translocates from the cytosol to the nucleoplasm - Drosophila melanogaster
inferredFrom	[Reaction:R-HSA-9865196] p-Y393-ABL1 phosphorylates tyrosine-407 of YAP1 - Homo sapiens
input	[EntityWithAccessionedSequence:R-DME-1253345] yki [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	p-Y393-ABL1 phosphorylates tyrosine-407 of YAP1
output	[EntityWithAccessionedSequence:R-DME-9865208] phospho-yki [cytosol]
precedingEvent	[BlackBoxEvent:R-DME-9865184] Phosphorylation of ABL1 on tyrosine-393 in response to oscillatory shear stress - Drosophila melanogaster [Reaction:R-DME-9865226] PP2A dephosphorylates serine-127 of YAP1 - Drosophila melanogaster
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-9865196
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-9860927] Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells
(precedingEvent)	[BlackBoxEvent:R-DME-9865176] p-Y407-YAP1 translocates from the cytosol to the nucleoplasm
(inferredTo)	[Reaction:R-HSA-9865196] p-Y393-ABL1 phosphorylates tyrosine-407 of YAP1