Reactome | Ciprofloxacin ADME

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Ciprofloxacin ADME Show undefined attributes

created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10913382
displayName	Ciprofloxacin ADME
eventOf	[TopLevelPathway:R-DME-9748784] Drug ADME - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-DME-9794270] SLCO1A2 transports Cipro(1+) into the cytosol - Drosophila melanogaster [Reaction:R-DME-9794523] SLC22A1 transports Cipro into renal cell - Drosophila melanogaster [Reaction:R-DME-9795207] SLC22A1 transports Cipro into hepatic cell - Drosophila melanogaster [Reaction:R-DME-9794572] ABCG2 transports Cipro from hepatic cell to extracellular space - Drosophila melanogaster [Reaction:R-DME-9794120] ABCG2 transports Cipro from intestinal cell to extracellular space - Drosophila melanogaster
inferredFrom	[Pathway:R-HSA-9793528] Ciprofloxacin ADME - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Ciprofloxacin ADME
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:56210] Drosophila melanogaster
stId	R-DME-9793528
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[TopLevelPathway:R-DME-9748784] Drug ADME
(inferredTo)	[Pathway:R-HSA-9793528] Ciprofloxacin ADME

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