Reactome | ZEB1 recruits SETD8 to CDH1 gene promoter

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10905476
displayName	ZEB1 recruits SETD8 to CDH1 gene promoter
eventOf	[Pathway:R-DME-9764725] Negative Regulation of CDH1 Gene Transcription - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9765791] ZEB1 recruits SETD8 to CDH1 gene promoter - Homo sapiens
input	[EntityWithAccessionedSequence:R-DME-417142] SETD8 [nucleoplasm] [Complex:R-DME-9793459] ZEB1:CDH1 gene [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	ZEB1 recruits SETD8 to CDH1 gene promoter
output	[Complex:R-DME-9931117] SETD8:ZEB1:CDH1 gene [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-9765791
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DME-9764725] Negative Regulation of CDH1 Gene Transcription
(inferredTo)	[Reaction:R-HSA-9765791] ZEB1 recruits SETD8 to CDH1 gene promoter

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