Reactome | SPHK2 binds SPHK2 inhibitors

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10904507
displayName	SPHK2 binds SPHK2 inhibitors
eventOf	[Pathway:R-DME-1660661] Sphingolipid de novo biosynthesis - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9695917] SPHK2 binds SPHK2 inhibitors - Homo sapiens
input	[DefinedSet:R-DME-428236-3] Homologues of SPHK2 [cytosol] [CandidateSet:R-ALL-9695954] SPHK2 inhibitors [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	SPHK2 binds SPHK2 inhibitors
output	[Complex:R-DME-9695910] SPHK2:SPHK2 inhibitors [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-9695917
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DME-1660661] Sphingolipid de novo biosynthesis
(inferredTo)	[Reaction:R-HSA-9695917] SPHK2 binds SPHK2 inhibitors

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