Reactome | mTORC1 binds RHEB:GTP

Schema > Reaction > Entries

mTORC1 binds RHEB:GTP Show undefined attributes

category	binding
compartment	[Compartment:17938] lysosomal membrane
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10903787
displayName	mTORC1 binds RHEB:GTP
eventOf	[Pathway:R-DME-9639288] Amino acids regulate mTORC1 - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9646468] mTORC1 binds RHEB:GTP - Homo sapiens
input	[Complex:R-DME-165189] RHEB:GTP [lysosomal membrane] [Complex:R-DME-9645607] v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	mTORC1 binds RHEB:GTP
output	[Complex:R-DME-9646467] v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane]
precedingEvent	[Reaction:R-DME-9645608] v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 - Drosophila melanogaster
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-9646468
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-9639288] Amino acids regulate mTORC1
(inferredTo)	[Reaction:R-HSA-9646468] mTORC1 binds RHEB:GTP