Reactome | PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GTP [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10903471
displayName	PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GTP [plasma membrane]
hasComponent	[Complex:R-DME-109783] p21 RAS:GTP [plasma membrane] [Complex:R-DME-9632853] PDPK1:PIP3:pS, p-T410 PRKCZ [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-9632904] PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GTP [plasma membrane] - Homo sapiens
maxDepth	4
name	PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GTP
positivelyRegulates	[PositiveRegulation:10903474] Positive regulation by 'PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GTP [plasma membrane]'
producedByEvent	[BlackBoxEvent:R-DME-9632918] PRKCZ stimulates RAS nucleotide exchange in response to estrogen - Drosophila melanogaster
schemaClass	Complex
species	[Species:56210] Drosophila melanogaster
stId	R-DME-9632904
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(regulator)	[PositiveRegulation:10903474] Positive regulation by 'PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GTP [plasma membrane]'
(output)	[BlackBoxEvent:R-DME-9632918] PRKCZ stimulates RAS nucleotide exchange in response to estrogen
(inferredTo)	[Complex:R-HSA-9632904] PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GTP [plasma membrane]

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