Reactome | RAN stimulates fusion of nuclear envelope (NE) membranes

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RAN stimulates fusion of nuclear envelope (NE) membranes Show undefined attributes

catalystActivity	[CatalystActivity:10903224] GTPase activator activity of SUMO1:RANGAP1 homodimer [nuclear envelope]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:13231] nuclear envelope
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10903226
displayName	RAN stimulates fusion of nuclear envelope (NE) membranes
eventOf	[Pathway:R-DME-9615933] Postmitotic nuclear pore complex (NPC) reformation - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9624893] RAN stimulates fusion of nuclear envelope (NE) membranes - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [Complex:R-DME-9624877] RAN:GTP:Nuclear envelope vesicles [nuclear envelope]
isInDisease	false
isInferred	true
maxDepth	1
name	RAN stimulates fusion of nuclear envelope (NE) membranes
output	[OtherEntity:R-ALL-9624890] Fused nuclear envelope vesicles [nuclear envelope] [SimpleEntity:R-ALL-29372] Pi [cytosol] [Complex:R-DME-206617] RAN:GDP [cytosol]
precedingEvent	[Reaction:R-DME-9624876] RAN:GTP recruits nuclear envelope (NE) membranes - Drosophila melanogaster
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-9624893
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-9615933] Postmitotic nuclear pore complex (NPC) reformation
(inferredTo)	[Reaction:R-HSA-9624893] RAN stimulates fusion of nuclear envelope (NE) membranes

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