Reactome | Co-repressor complex dissociates from the transcription unit of the ABCA1 gene

Schema > Reaction > Entries

Co-repressor complex dissociates from the transcription unit of the ABCA1 gene Show undefined attributes

category	dissociation
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10902327
displayName	Co-repressor complex dissociates from the transcription unit of the ABCA1 gene
eventOf	[Pathway:R-DME-9029569] NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DME-9029551] NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex - Drosophila melanogaster
inferredFrom	[Reaction:R-HSA-9024334] Co-repressor complex dissociates from the transcription unit of the ABCA1 gene - Homo sapiens
input	[Complex:R-DME-9024368] ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands:NCOR:GPS2:TBL1:HDAC3 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Co-repressor complex dissociates from the transcription unit of the ABCA1 gene
output	[Complex:R-DME-9024330] ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] [Complex:R-DME-9024373] NCOR:GPS2:TBL1:HDAC3 [nucleoplasm]
precedingEvent	[Reaction:R-DME-9024326] Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex - Drosophila melanogaster
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-9024334
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-9029569] NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
(precedingEvent)	[Reaction:R-DME-9029551] NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex
(inferredTo)	[Reaction:R-HSA-9024334] Co-repressor complex dissociates from the transcription unit of the ABCA1 gene

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