Reactome | Interleukin-23 signaling

Schema > Pathway > Entries

created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10913136
displayName	Interleukin-23 signaling
eventOf	[Pathway:R-DME-447115] Interleukin-12 family signaling - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:2266300] interleukin-23-mediated signaling pathway
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DME-8950780] p-Y705-STAT3 binds p-Y693-STAT4 - Drosophila melanogaster [BlackBoxEvent:R-DME-8950724] p-Y705-STAT3:p-Y693-STAT4 translocates to the nucleus - Drosophila melanogaster
inferredFrom	[Pathway:R-HSA-9020933] Interleukin-23 signaling - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Interleukin-23 signaling
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:56210] Drosophila melanogaster
stId	R-DME-9020933
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DME-447115] Interleukin-12 family signaling
(inferredTo)	[Pathway:R-HSA-9020933] Interleukin-23 signaling

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