Reactome | EP300 is recruited to MYC and BCL2 genes

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EP300 is recruited to MYC and BCL2 genes Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10901408
displayName	EP300 is recruited to MYC and BCL2 genes
eventOf	[Pathway:R-DME-9018519] Estrogen-dependent gene expression - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9011981] EP300 is recruited to MYC and BCL2 genes - Homo sapiens
input	[Complex:R-DME-9011896] MYC gene, BCL2 gene:HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] [EntityWithAccessionedSequence:R-DME-381325] nej [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	EP300 is recruited to MYC and BCL2 genes
output	[Complex:R-DME-9011897] MYC gene, BCL2 gene:HIST1H2AC nucleosome:ESR1:ESTG:EP300 [nucleoplasm]
precedingEvent	[Reaction:R-DME-9011985] KDM1A demethylates H3 on MYC and BCL genes in response to estrogen - Drosophila melanogaster
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-9011981
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-9018519] Estrogen-dependent gene expression
(inferredTo)	[Reaction:R-HSA-9011981] EP300 is recruited to MYC and BCL2 genes

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