Reactome | NCOA1 binds ESR1:estrogen:TGFA gene

Schema > Reaction > Entries

NCOA1 binds ESR1:estrogen:TGFA gene Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10901145
displayName	NCOA1 binds ESR1:estrogen:TGFA gene
eventOf	[Pathway:R-DME-9018519] Estrogen-dependent gene expression - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DME-9023884] NCOA1 recruits EP300 to TGFA promoter - Drosophila melanogaster
inferredFrom	[Reaction:R-HSA-9008270] NCOA1 binds ESR1:estrogen:TGFA gene - Homo sapiens
input	[Complex:R-DME-9008287] ESR1 dimer:estrogen:TGFA gene promoter [nucleoplasm] [EntityWithAccessionedSequence:R-DME-442496] tai [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	NCOA1 binds ESR1:estrogen:TGFA gene
output	[Complex:R-DME-9023832] ESR1 dimer:estrogen:TFGA gene:NCOA1 [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-9008270
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-9018519] Estrogen-dependent gene expression
(precedingEvent)	[Reaction:R-DME-9023884] NCOA1 recruits EP300 to TGFA promoter
(inferredTo)	[Reaction:R-HSA-9008270] NCOA1 binds ESR1:estrogen:TGFA gene

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