Reactome | RUNX2 binds SOX9

Schema > Reaction > Entries

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10901009
displayName	RUNX2 binds SOX9
eventOf	[Pathway:R-DME-8878166] Transcriptional regulation by RUNX2 - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8985343] RUNX2 binds SOX9 - Homo sapiens
input	[CandidateSet:R-DME-9007751] RUNX2 [nucleoplasm] [EntityWithAccessionedSequence:R-DME-3214954] Sox100B [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	RUNX2 binds SOX9
output	[Complex:R-DME-8985335] RUNX2:SOX9 [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-8985343
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DME-8878166] Transcriptional regulation by RUNX2
(inferredTo)	[Reaction:R-HSA-8985343] RUNX2 binds SOX9