Reactome | p-VAV family:PIP3:RAC1:GDP [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10876544] guanyl-nucleotide exchange factor activity of p-VAV family:PIP3:RAC1:GDP [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-DME-5218850] VAV exchanges GTP for GDP on RAC1, activating it - Drosophila melanogaster
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10876541
displayName	p-VAV family:PIP3:RAC1:GDP [plasma membrane]
hasComponent	[Complex:R-DME-5218789] p-VAV family:PIP3 [plasma membrane] [Complex:R-DME-5674631] RAC1:GDP [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-8951587] p-VAV family:PIP3:RAC1:GDP [plasma membrane] - Homo sapiens
maxDepth	3
name	p-VAV family:PIP3:RAC1:GDP
producedByEvent	[Reaction:R-DME-8951586] p-VAV family:PIP3 binds RAC1:GDP - Drosophila melanogaster
schemaClass	Complex
species	[Species:56210] Drosophila melanogaster
stId	R-DME-8951587
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-DME-5218850] VAV exchanges GTP for GDP on RAC1, activating it
(physicalEntity)	[CatalystActivity:10876544] guanyl-nucleotide exchange factor activity of p-VAV family:PIP3:RAC1:GDP [plasma membrane]
(output)	[Reaction:R-DME-8951586] p-VAV family:PIP3 binds RAC1:GDP
(inferredTo)	[Complex:R-HSA-8951587] p-VAV family:PIP3:RAC1:GDP [plasma membrane]

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