Reactome | hp-IRAK1:p-Pellino, IRAK4:p-Pellino bind UBE2N:UBE2V1

Schema > BlackBoxEvent > Entries

category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10899088
displayName	hp-IRAK1:p-Pellino, IRAK4:p-Pellino bind UBE2N:UBE2V1
eventOf	[Pathway:R-DME-9020702] Interleukin-1 signaling - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-8948063] hp-IRAK1:p-Pellino, IRAK4:p-Pellino bind UBE2N:UBE2V1 - Homo sapiens
input	[DefinedSet:R-DME-451425] hp-IRAK1:p-Pellino, IRAK4:p-Pellino [cytosol] 2 × [Complex:R-DME-8948017] UBE2N:UBE2V1:K63polyUb [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	hp-IRAK1:p-Pellino, IRAK4:p-Pellino bind UBE2N:UBE2V1
output	[DefinedSet:R-DME-8948067] IRAK1:Pellino:E2 complexes [cytosol]
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:56210] Drosophila melanogaster
stId	R-DME-8948063
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DME-9020702] Interleukin-1 signaling
(inferredTo)	[BlackBoxEvent:R-HSA-8948063] hp-IRAK1:p-Pellino, IRAK4:p-Pellino bind UBE2N:UBE2V1

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