Reactome | PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10895562] 1-phosphatidylinositol-4-phosphate 3-kinase activity of PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-DME-8867754] F- and N- BAR domain proteins bind the clathrin-coated pit - Drosophila melanogaster
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10895494
displayName	PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane]
hasComponent	[Complex:R-DME-8867753] PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] [EntityWithAccessionedSequence:R-DME-1604624] Pi3K68D [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-8868051] PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] - Homo sapiens
maxDepth	10
name	PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A
producedByEvent	[Reaction:R-DME-8868071] Clathrin recruits PIK3C2A - Drosophila melanogaster
schemaClass	Complex
species	[Species:56210] Drosophila melanogaster
stId	R-DME-8868051
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(physicalEntity)	[CatalystActivity:10895562] 1-phosphatidylinositol-4-phosphate 3-kinase activity of PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane]
(input)	[Reaction:R-DME-8867754] F- and N- BAR domain proteins bind the clathrin-coated pit
(output)	[Reaction:R-DME-8868071] Clathrin recruits PIK3C2A
(inferredTo)	[Complex:R-HSA-8868051] PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane]

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