Reactome | 2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2 [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-DME-8855523] 2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] - Drosophila melanogaster
consumedByEvent	[BlackBoxEvent:R-DME-8854905] p-5Y-GAB in the RET-GRB2-GAB complexes binds p85-PI3K - Drosophila melanogaster
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10894402
displayName	2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2 [plasma membrane]
hasComponent	[DefinedSet:R-DME-8854907] 2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] [EntityWithAccessionedSequence:R-DME-180344] phospho-dos [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-8855302] 2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2 [plasma membrane] - Homo sapiens
maxDepth	6
name	2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2
producedByEvent	[BlackBoxEvent:R-DME-8853774] GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated - Drosophila melanogaster
schemaClass	Complex
species	[Species:56210] Drosophila melanogaster
stId	R-DME-8855302
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[BlackBoxEvent:R-DME-8854905] p-5Y-GAB in the RET-GRB2-GAB complexes binds p85-PI3K
(hasComponent)	[Complex:R-DME-8855523] 2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2:p85-containing Class 1A PI3Ks [plasma membrane]
(output)	[BlackBoxEvent:R-DME-8853774] GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated
(inferredTo)	[Complex:R-HSA-8855302] 2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2 [plasma membrane]

Cite Us!