Reactome | RAB43:GTP binds USP8NL

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RAB43:GTP binds USP8NL Show undefined attributes

category	binding
compartment	[Compartment:263163] trans-Golgi network membrane
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10893310
displayName	RAB43:GTP binds USP8NL
eventOf	[Pathway:R-DME-6811440] Retrograde transport at the Trans-Golgi-Network - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DME-8847534] RAB43 hydrolyses GTP - Drosophila melanogaster
inferredFrom	[Reaction:R-HSA-8847537] RAB43:GTP binds USP8NL - Homo sapiens
input	[Complex:R-DME-8847528] RAB43:GTP [trans-Golgi network membrane] [EntityWithAccessionedSequence:R-DME-6813922] RN-tre [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	RAB43:GTP binds USP8NL
output	[Complex:R-DME-8847526] RAB43:GTP:USP6NL [trans-Golgi network membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-8847537
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-6811440] Retrograde transport at the Trans-Golgi-Network
(precedingEvent)	[Reaction:R-DME-8847534] RAB43 hydrolyses GTP
(inferredTo)	[Reaction:R-HSA-8847537] RAB43:GTP binds USP8NL