Reactome | Gastrin-CREB signalling pathway via PKC and MAPK

Schema > Pathway > Entries

created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10911598
displayName	Gastrin-CREB signalling pathway via PKC and MAPK
eventOf	[Pathway:R-DME-416476] G alpha (q) signalling events - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-DME-2179392] EGFR Transactivation by Gastrin - Drosophila melanogaster [Reaction:R-DME-198746] ERK1/2/5 activate RSK1/2/3 - Drosophila melanogaster [Reaction:R-DME-199895] RSK1/2/3 phosphorylates CREB at Serine 119 - Drosophila melanogaster
inferredFrom	[Pathway:R-HSA-881907] Gastrin-CREB signalling pathway via PKC and MAPK - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Gastrin-CREB signalling pathway via PKC and MAPK
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:56210] Drosophila melanogaster
stId	R-DME-881907
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(inferredTo)	[Pathway:R-HSA-881907] Gastrin-CREB signalling pathway via PKC and MAPK
(hasEvent)	[Pathway:R-DME-416476] G alpha (q) signalling events

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