Reactome | ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate

Schema > Reaction > Entries

ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate Show undefined attributes

catalystActivity	[CatalystActivity:10831535] transketolase activity of TKT dimer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10831537
displayName	ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
eventOf	[Pathway:R-DME-71336] Pentose phosphate pathway - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DME-71334] sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate - Drosophila melanogaster
inferredFrom	[Reaction:R-HSA-71324] ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate - Homo sapiens
input	[SimpleEntity:R-ALL-73578] R5P [cytosol] [SimpleEntity:R-ALL-29790] XY5P [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate TKT dimer transfers two-carbon ketol group onto XY5P
output	[SimpleEntity:R-ALL-29578] GA3P [cytosol] [SimpleEntity:R-ALL-29882] SH7P [cytosol]
precedingEvent	[Reaction:R-DME-71306] RPIA isomerizes D-ribulose 5-phosphate to ribose 5-phosphate - Drosophila melanogaster [Reaction:R-DME-71303] RPE dimers isomerise RU5P to XY5P - Drosophila melanogaster [Reaction:R-DME-5662466] XYLB phosphorylates D-xylulose - Drosophila melanogaster [Reaction:R-DME-8955844] RBKS phosphorylates ribose to R5P - Drosophila melanogaster
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-71324
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-71336] Pentose phosphate pathway
(precedingEvent)	[Reaction:R-DME-71334] sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate
(inferredTo)	[Reaction:R-HSA-71324] ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate

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