Reactome | PERP binds desmosomes

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10893271
displayName	PERP binds desmosomes
eventOf	[Pathway:R-DME-6809371] Formation of the cornified envelope - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-6814695] PERP binds desmosomes - Homo sapiens
input	[EntityWithAccessionedSequence:R-DME-6800837] CG6982 [plasma membrane] [Complex:R-DME-6814388] Desmosome [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	PERP binds desmosomes
output	[Complex:R-DME-8848046] Desmosome:PERP [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-6814695
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DME-6809371] Formation of the cornified envelope
(inferredTo)	[Reaction:R-HSA-6814695] PERP binds desmosomes