Reactome | SNAPs and NSF hexamer bind cis-SNARE at the TGN

Schema > Reaction > Entries

SNAPs and NSF hexamer bind cis-SNARE at the TGN Show undefined attributes

category	binding
compartment	[Compartment:263163] trans-Golgi network membrane
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10893205
displayName	SNAPs and NSF hexamer bind cis-SNARE at the TGN
eventOf	[Pathway:R-DME-6811440] Retrograde transport at the Trans-Golgi-Network - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DME-6814678] ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN - Drosophila melanogaster
inferredFrom	[Reaction:R-HSA-6814676] SNAPs and NSF hexamer bind cis-SNARE at the TGN - Homo sapiens
input	[Complex:R-DME-2193131] NSF hexamer [cytosol] 3 × [CandidateSet:R-DME-5694313] SNAPs [cytosol] [Complex:R-DME-6814652] STX10:STX16:VTI1A:VAMP3 [trans-Golgi network membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	SNAPs and NSF hexamer bind cis-SNARE at the TGN
output	[Complex:R-DME-6814654] STX10:STX16:VTI1A:VAMP3:NSF hexamer:SNAPs [trans-Golgi network membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-6814676
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-6811440] Retrograde transport at the Trans-Golgi-Network
(precedingEvent)	[Reaction:R-DME-6814678] ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN
(inferredTo)	[Reaction:R-HSA-6814676] SNAPs and NSF hexamer bind cis-SNARE at the TGN

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