Reactome | RNA polymerase II transcribes snRNA genes

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RNA polymerase II transcribes snRNA genes Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10655440] Wright, Adam, 2024-03-08
dbId	10739572
displayName	RNA polymerase II transcribes snRNA genes
eventOf	[Pathway:R-DME-73857] RNA Polymerase II Transcription - Drosophila melanogaster
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:81481] snRNA transcription by RNA polymerase II
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-DME-6810238] RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) - Drosophila melanogaster [Reaction:R-DME-6810233] CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter - Drosophila melanogaster [BlackBoxEvent:R-DME-6814549] Pre-snRNA transcript initiation, Integrator binding, LEC binding - Drosophila melanogaster [BlackBoxEvent:R-DME-6814559] Pre-snRNA is elongated and capped with 7-methylguanosine - Drosophila melanogaster [Reaction:R-DME-6814885] CBCAP complex binds 7-methylguanosine cap of snRNA - Drosophila melanogaster [BlackBoxEvent:R-DME-6814555] Integrator complex processes the 3' end of snRNA - Drosophila melanogaster
inferredFrom	[Pathway:R-HSA-6807505] RNA polymerase II transcribes snRNA genes - Homo sapiens
isInDisease	false
isInferred	true
name	RNA polymerase II transcribes snRNA genes
releaseDate	2024-03-27
schemaClass	Pathway
species	[Species:56210] Drosophila melanogaster
stId	R-DME-6807505
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEncapsulatedEvent)	[TopLevelPathway:R-DME-74160] Gene expression (Transcription)
(hasEvent)	[Pathway:R-DME-73857] RNA Polymerase II Transcription
(inferredTo)	[Pathway:R-HSA-6807505] RNA polymerase II transcribes snRNA genes

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