Reactome | SFN dimerizes

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10891548
displayName	SFN dimerizes
eventOf	[Pathway:R-DME-6804114] TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DME-6803875] SFN dimer binds CDK1 and CCNB1 - Drosophila melanogaster
inferredFrom	[Reaction:R-HSA-6803890] SFN dimerizes - Homo sapiens
input	2 × [EntityWithAccessionedSequence:R-DME-1445105] 14-3-3zeta [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	SFN dimerizes
output	[Complex:R-DME-2262716] SFN dimer [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-6803890
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DME-6804114] TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
(precedingEvent)	[Reaction:R-DME-6803875] SFN dimer binds CDK1 and CCNB1
(inferredTo)	[Reaction:R-HSA-6803890] SFN dimerizes