Reactome | COP9 signalosome [nucleoplasm]

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COP9 signalosome [nucleoplasm] Show undefined attributes

catalystActivities	[CatalystActivity:10900415] deNEDDylase activity of COP9 signalosome [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-DME-6781842] ERCC8:DDB1:CUL4:RBX1:COP9 Signalosome [nucleoplasm] - Drosophila melanogaster [Complex:R-DME-5697031] UV-DDB:COP9 Signalosome [nucleoplasm] - Drosophila melanogaster
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10883575
displayName	COP9 signalosome [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-DME-5697012] alien [nucleoplasm] [EntityWithAccessionedSequence:R-DME-5697019] COPS5 [nucleoplasm] [EntityWithAccessionedSequence:R-DME-5697010] CSN1b [nucleoplasm] [EntityWithAccessionedSequence:R-DME-5697017] CSN3 [nucleoplasm] [EntityWithAccessionedSequence:R-DME-5697020] CSN4 [nucleoplasm] [EntityWithAccessionedSequence:R-DME-5697026] CSN6 [nucleoplasm] [EntityWithAccessionedSequence:R-DME-5697011] CSN7 [nucleoplasm] [EntityWithAccessionedSequence:R-DME-5697014] CSN8 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-5697024] COP9 signalosome [nucleoplasm] - Homo sapiens
maxDepth	2
name	COP9 signalosome
producedByEvent	[Reaction:R-DME-6781833] ERCC8 (CSA) binds stalled RNA Pol II - Drosophila melanogaster [Reaction:R-DME-5691006] XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site - Drosophila melanogaster
schemaClass	Complex
species	[Species:56210] Drosophila melanogaster
stId	R-DME-5697024
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(physicalEntity)	[CatalystActivity:10900415] deNEDDylase activity of COP9 signalosome [nucleoplasm]
(output)	[Reaction:R-DME-6781833] ERCC8 (CSA) binds stalled RNA Pol II [Reaction:R-DME-5691006] XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site
(hasComponent)	[Complex:R-DME-6781842] ERCC8:DDB1:CUL4:RBX1:COP9 Signalosome [nucleoplasm] [Complex:R-DME-5697031] UV-DDB:COP9 Signalosome [nucleoplasm]
(inferredTo)	[Complex:R-HSA-5697024] COP9 signalosome [nucleoplasm]

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