Reactome | ATG12 binds ATG7 dimer

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ATG12 binds ATG7 dimer Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10881787
displayName	ATG12 binds ATG7 dimer
eventOf	[Pathway:R-DME-1632852] Macroautophagy - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DME-9020616] ATG12 forms a thioester bond with ATG7 dimer - Drosophila melanogaster
inferredFrom	[Reaction:R-HSA-5681980] ATG12 binds ATG7 dimer - Homo sapiens
input	[EntityWithAccessionedSequence:R-DME-936011] Atg12 [cytosol] [Complex:R-DME-5682892] ATG7 dimer [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	ATG12 binds ATG7 dimer
output	[Complex:R-DME-9020617] ATG12:ATG7 dimer [cytosol]
precedingEvent	[Reaction:R-DME-5683593] ATG7:ATG3:LC3 dissociates - Drosophila melanogaster
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-5681980
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-1632852] Macroautophagy
(precedingEvent)	[Reaction:R-DME-9020616] ATG12 forms a thioester bond with ATG7 dimer
(inferredTo)	[Reaction:R-HSA-5681980] ATG12 binds ATG7 dimer

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