Reactome | SPOP:CUL3:RBX1 [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-DME-5635087] 2p-GLI:SPOP:CUL3:RBX1 [nucleoplasm] - Drosophila melanogaster [Complex:R-DME-5635095] ub-2p-GLI2,3:SPOP:CUL3:RBX1 [nucleoplasm] - Drosophila melanogaster
consumedByEvent	[Reaction:R-DME-5635855] phosphorylated GLI proteins bind SPOP:CUL3:RBX1 - Drosophila melanogaster
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10879877
displayName	SPOP:CUL3:RBX1 [nucleoplasm]
hasComponent	2 × [EntityWithAccessionedSequence:R-DME-5635033] Cul3 [nucleoplasm] 2 × [EntityWithAccessionedSequence:R-DME-1234142] RBX1 [nucleoplasm] [CandidateSet:R-DME-5635065] SPOP dimer [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-5635071] SPOP:CUL3:RBX1 [nucleoplasm] - Homo sapiens
maxDepth	5
name	SPOP:CUL3:RBX1
producedByEvent	[BlackBoxEvent:R-DME-5635854] GLI2,3 are degraded by the proteasome - Drosophila melanogaster
schemaClass	Complex
species	[Species:56210] Drosophila melanogaster
stId	R-DME-5635071
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[BlackBoxEvent:R-DME-5635854] GLI2,3 are degraded by the proteasome
(inferredTo)	[Complex:R-HSA-5635071] SPOP:CUL3:RBX1 [nucleoplasm]
(input)	[Reaction:R-DME-5635855] phosphorylated GLI proteins bind SPOP:CUL3:RBX1
(hasComponent)	[Complex:R-DME-5635095] ub-2p-GLI2,3:SPOP:CUL3:RBX1 [nucleoplasm] [Complex:R-DME-5635087] 2p-GLI:SPOP:CUL3:RBX1 [nucleoplasm]