Reactome | Phosphorylated PKN1 binds androgen receptor (AR)

Schema > Reaction > Entries

Phosphorylated PKN1 binds androgen receptor (AR) Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10879469
displayName	Phosphorylated PKN1 binds androgen receptor (AR)
eventOf	[Pathway:R-DME-5625886] Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DME-5625738] p-T774-PKN1:AR:Androgen complex translocates to the nucleus - Drosophila melanogaster
inferredFrom	[Reaction:R-HSA-5625717] Phosphorylated PKN1 binds androgen receptor (AR) - Homo sapiens
input	[Complex:R-DME-5625732] AR:Androgens [cytosol] [EntityWithAccessionedSequence:R-DME-5623651] phospho-p-T774-PKN1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Phosphorylated PKN1 binds androgen receptor (AR)
output	[Complex:R-DME-5625734] p-T774-PKN1:AR:Androgen [cytosol]
precedingEvent	[Reaction:R-DME-5623667] PDPK1 phosphorylates PKN1,2,3 - Drosophila melanogaster
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-5625717
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-5625886] Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
(precedingEvent)	[Reaction:R-DME-5625738] p-T774-PKN1:AR:Androgen complex translocates to the nucleus
(inferredTo)	[Reaction:R-HSA-5625717] Phosphorylated PKN1 binds androgen receptor (AR)

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