Reactome | Phase 2 - plateau phase

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Phase 2 - plateau phase Show undefined attributes

created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10912766
displayName	Phase 2 - plateau phase
eventOf	[Pathway:R-DME-5576891] Cardiac conduction - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Pathway:R-DME-5576890] Phase 3 - rapid repolarisation - Drosophila melanogaster
goBiologicalProcess	[GO_BiologicalProcess:1042616] cardiac conduction
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DME-5577213] LTCC multimer transports Ca2+ from extracellular region to cytosol - Drosophila melanogaster [Reaction:R-DME-9614031] Class IV antihypertensives bind LTCC multimer - Drosophila melanogaster
inferredFrom	[Pathway:R-HSA-5576893] Phase 2 - plateau phase - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Phase 2 - plateau phase
precedingEvent	[Pathway:R-DME-5576894] Phase 1 - inactivation of fast Na+ channels - Drosophila melanogaster
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:56210] Drosophila melanogaster
stId	R-DME-5576893
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-5576891] Cardiac conduction
(precedingEvent)	[Pathway:R-DME-5576890] Phase 3 - rapid repolarisation
(inferredTo)	[Pathway:R-HSA-5576893] Phase 2 - plateau phase

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