Reactome | Mismatch Repair

Schema > Pathway > Entries

created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10912742
displayName	Mismatch Repair
eventOf	[TopLevelPathway:R-DME-73894] DNA Repair - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:17157] mismatch repair
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-DME-5358565] Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) - Drosophila melanogaster [Pathway:R-DME-5358606] Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) - Drosophila melanogaster
inferredFrom	[Pathway:R-HSA-5358508] Mismatch Repair - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Mismatch Repair MMR
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:56210] Drosophila melanogaster
stId	R-DME-5358508
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[TopLevelPathway:R-DME-73894] DNA Repair
(hasEncapsulatedEvent)	[Pathway:R-DME-6796648] TP53 Regulates Transcription of DNA Repair Genes
(inferredTo)	[Pathway:R-HSA-5358508] Mismatch Repair

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