Reactome | YKI is phosphorylated by and then dissociates from phosphorylated WTS

Schema > Reaction > Entries

YKI is phosphorylated by and then dissociates from phosphorylated WTS Show undefined attributes

authored	[InstanceEdit:390144] Williams, MG, 2009-01-23 09:43:46
catalystActivity	[CatalystActivity:451882] protein serine/threonine kinase activity of Phospho HPO dimer:Phospho SAV:Phospho (2 sites) WTS:YKI:Phospho MATS [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:390104] Williams, MG, 2009-01-23 09:54:10
dbId	390044
displayName	YKI is phosphorylated by and then dissociates from phosphorylated WTS
edited	[InstanceEdit:390104] Williams, MG, 2009-01-23 09:54:10
eventOf	[Pathway:R-DME-390098] Phosphorylation-dependent inhibition of YKI - Drosophila melanogaster
figure	[Figure:451877] /figures/DrosBHippoW13.jpg
followingEvent	[Reaction:R-DME-390078] 14-3-3 dimer binds to phosphorylated YKI - Drosophila melanogaster [Reaction:R-DME-390061] YKI binds to phosphorylated WTS - Drosophila melanogaster [Reaction:R-DME-390120] Phosphorylated HPO dimer phosphorylates TH - Drosophila melanogaster
input	3 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-DME-390067] Phospho HPO dimer:Phospho SAV:Phospho (2 sites) WTS:YKI:Phospho MATS [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:390065] The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP [LiteratureReference:390048] Elucidation of a universal size-control mechanism in Drosophila and mammals [LiteratureReference:390111] In vivo regulation of Yorkie phosphorylation and localization [LiteratureReference:451830] In vivo analysis of Yorkie phosphorylation sites
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	YKI is phosphorylated by and then dissociates from phosphorylated WTS
output	3 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-DME-390068] Phospho HPO dimer:Phospho SAV:Phospho (2 sites) WTS:Phospho MATS [cytosol] [EntityWithAccessionedSequence:R-DME-390064] Phospho YKI [cytosol]
precedingEvent	[Reaction:R-DME-390061] YKI binds to phosphorylated WTS - Drosophila melanogaster
releaseDate	2010-07-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:909538] Irvine, KD, 2009-11-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-390044
summation	[Summation:390153] The transcription factor Yorkie (YKI) is phosphorylated at S...

Referrals

(precedingEvent)	[Reaction:R-DME-390120] Phosphorylated HPO dimer phosphorylates TH [Reaction:R-DME-390078] 14-3-3 dimer binds to phosphorylated YKI [Reaction:R-DME-390061] YKI binds to phosphorylated WTS
(hasEvent)	[Pathway:R-DME-390098] Phosphorylation-dependent inhibition of YKI

Cite Us!