Reactome | AMPK is dephosphorylated

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AMPK is dephosphorylated Show undefined attributes

catalystActivity	[CatalystActivity:10848822] protein serine/threonine phosphatase activity of PPM1A [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10848824
displayName	AMPK is dephosphorylated
eventOf	[Pathway:R-DME-380972] Energy dependent regulation of mTOR by LKB1-AMPK - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-380949] AMPK is dephosphorylated - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [Complex:R-DME-380934] p-AMPK heterotrimer [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	AMPK is dephosphorylated
output	[Complex:R-DME-380961] AMPK heterotrimer [cytosol] [SimpleEntity:R-ALL-29372] Pi [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-380949
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-380972] Energy dependent regulation of mTOR by LKB1-AMPK
(inferredTo)	[Reaction:R-HSA-380949] AMPK is dephosphorylated

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