Reactome | Serotonin loaded synaptic vesicle docking and priming

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Serotonin loaded synaptic vesicle docking and priming Show undefined attributes

catalystActivity	[CatalystActivity:10848800] SNARE binding activity of Serotonin loaded synaptic vesicle [clathrin-sculpted monoamine transport vesicle membrane]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:374940] clathrin-sculpted monoamine transport vesicle membrane [Compartment:70101] cytosol
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10848802
displayName	Serotonin loaded synaptic vesicle docking and priming
eventOf	[Pathway:R-DME-181429] Serotonin Neurotransmitter Release Cycle - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DME-380901] Release of docked serotonin loaded synaptic vesicle - Drosophila melanogaster
inferredFrom	[Reaction:R-HSA-380905] Serotonin loaded synaptic vesicle docking and priming - Homo sapiens
input	[EntityWithAccessionedSequence:R-DME-210385] cpx [cytosol] [DefinedSet:R-DME-2029017-3] Homologues of SNAP25 [plasma membrane] [Complex:R-DME-210374] RIMS1:UNC13B:BZRAP1:Alpha-liprin [plasma membrane] [EntityWithAccessionedSequence:R-DME-210514] Rop [cytosol] [Complex:R-DME-380903] Serotonin loaded synaptic vesicle [clathrin-sculpted monoamine transport vesicle membrane] [CandidateSet:R-DME-380576] Synapsin [clathrin-sculpted monoamine transport vesicle membrane] [EntityWithAccessionedSequence:R-DME-449128] Syx1A [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Serotonin loaded synaptic vesicle docking and priming
output	[Complex:R-DME-380900] Docked serotonin loaded synaptic vesicle [plasma membrane]
precedingEvent	[Reaction:R-DME-380586] loading of Serotonin in synaptic vesicles - Drosophila melanogaster
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-380905
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-181429] Serotonin Neurotransmitter Release Cycle
(precedingEvent)	[Reaction:R-DME-380901] Release of docked serotonin loaded synaptic vesicle
(inferredTo)	[Reaction:R-HSA-380905] Serotonin loaded synaptic vesicle docking and priming