Reactome | TGFB1:LAP1 [extracellular region]

Schema > Complex > Entries

compartment	[Compartment:984] extracellular region
componentOf	[Complex:R-DME-2396201] LTBP1:TGFB1:LAP1:LAP1-binding integrins [plasma membrane] - Drosophila melanogaster
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10840629
displayName	TGFB1:LAP1 [extracellular region]
hasComponent	[Complex:R-DME-170852] Dimeric TGFB1 [extracellular region] 2 × [EntityWithAccessionedSequence:R-DME-2395367] dpp [extracellular region]
inDisease	false
inferredFrom	[Complex:R-HSA-2395236] TGFB1:LAP1 [extracellular region] - Homo sapiens
maxDepth	3
memberOf	[DefinedSet:R-DME-2395330] TGFB:LAP [extracellular region] - Drosophila melanogaster
name	TGFB1:LAP1
producedByEvent	[BlackBoxEvent:R-DME-177107] Secretion and activation of the latent large complex of TGF-beta-1 - Drosophila melanogaster
schemaClass	Complex
species	[Species:56210] Drosophila melanogaster
stId	R-DME-2395236
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(hasComponent)	[Complex:R-DME-2396201] LTBP1:TGFB1:LAP1:LAP1-binding integrins [plasma membrane] [Complex:R-DME-9737594] LTBP1:TGFB1:LAP1 [extracellular region]
(output)	[BlackBoxEvent:R-DME-177107] Secretion and activation of the latent large complex of TGF-beta-1
(hasMember)	[DefinedSet:R-DME-2395330] TGFB:LAP [extracellular region]
(inferredTo)	[Complex:R-HSA-2395236] TGFB1:LAP1 [extracellular region]