Reactome | PRC2 (EZH2) Core [nucleoplasm]

Schema > Complex > Entries

PRC2 (EZH2) Core [nucleoplasm] Show undefined attributes

candidateOf	[CandidateSet:R-DME-8943822] PRC1.4,PRC2 (EZH2) core [nucleoplasm] - Drosophila melanogaster
catalystActivities	[CatalystActivity:10873024] histone H3K27 methyltransferase activity of PRC2 (EZH2) Core [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-DME-3211702] PRC2:Chromatin (5-methylcytosine, H3K27me3) [nucleoplasm] - Drosophila melanogaster [Complex:R-DME-5084071] PRC2 Core:Chromatin [nucleoplasm] - Drosophila melanogaster [Complex:R-DME-9815907] PRC2 (EZH2) Core:Nucleosome:CDH1 gene [nucleoplasm] - Drosophila melanogaster
consumedByEvent	[Reaction:R-DME-8954110] E2F6:TFDP1:EPC1 binds the PRC2 complex - Drosophila melanogaster
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10845940
displayName	PRC2 (EZH2) Core [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-DME-212223] Caf1-55 [nucleoplasm] [EntityWithAccessionedSequence:R-DME-212298] E(z) [nucleoplasm] [EntityWithAccessionedSequence:R-DME-212278] escl [nucleoplasm] [EntityWithAccessionedSequence:R-DME-212217] Su(z)12 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-212285] PRC2 (EZH2) Core [nucleoplasm] - Homo sapiens
maxDepth	2
memberOf	[DefinedSet:R-DME-5084084] PRC2 [nucleoplasm] - Drosophila melanogaster [DefinedSet:R-DME-9965980] PRC2 (EZH1,EZH2) core [nucleoplasm] - Drosophila melanogaster
name	PRC2 (EZH2) Core
producedByEvent	[Reaction:R-DME-3240957] Formation of PRC2-EZH2 complex - Drosophila melanogaster
schemaClass	Complex
species	[Species:56210] Drosophila melanogaster
stId	R-DME-212285
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(hasComponent)	[Complex:R-DME-3211702] PRC2:Chromatin (5-methylcytosine, H3K27me3) [nucleoplasm] [Complex:R-DME-5084072] PRC2:JARID2:MTF2 [nucleoplasm] [Complex:R-DME-5084089] PRC2:PHF1 [nucleoplasm] [Complex:R-DME-5084076] PRC2:PHF19 [nucleoplasm] [Complex:R-DME-5084071] PRC2 Core:Chromatin [nucleoplasm] [Complex:R-DME-5084065] PRC2 (EZH2) Core:AEBP2 [nucleoplasm] [Complex:R-DME-8954116] E2F6:TFDP1:EPC1:PRC2 (EZH2) core [nucleoplasm] [Complex:R-DME-9909625] PRC2(EZH2) Core:Nucleosome:CD274 gene promoter [nucleoplasm] [Complex:R-DME-9815907] PRC2 (EZH2) Core:Nucleosome:CDH1 gene [nucleoplasm] [Complex:R-DME-9815909] PRC2 (EZH2) Core:H3K27me3-Nucleosome:CDH1 gene [nucleoplasm]
(hasMember)	[DefinedSet:R-DME-9965980] PRC2 (EZH1,EZH2) core [nucleoplasm] [DefinedSet:R-DME-5084084] PRC2 [nucleoplasm]
(input)	[Reaction:R-DME-8954110] E2F6:TFDP1:EPC1 binds the PRC2 complex
(activeUnit)	[CatalystActivity:10905460] histone H3K27 methyltransferase activity of PRC2 (EZH2) Core:Nucleosome:CDH1 gene [nucleoplasm]
(physicalEntity)	[CatalystActivity:10873024] histone H3K27 methyltransferase activity of PRC2 (EZH2) Core [nucleoplasm]
(output)	[Reaction:R-DME-3240957] Formation of PRC2-EZH2 complex
(hasCandidate)	[CandidateSet:R-DME-8943822] PRC1.4,PRC2 (EZH2) core [nucleoplasm]
(inferredTo)	[Complex:R-HSA-212285] PRC2 (EZH2) Core [nucleoplasm]

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