Reactome | Toll pathway

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Toll pathway Show undefined attributes

authored	[InstanceEdit:386948] Williams, MG, 2007-07-11 16:49:12
created	[InstanceEdit:205654] Williams, MG, 2007-07-12 09:20:19
dbId	209449
displayName	Toll pathway
doi	10.3180/REACT_16344.1
edited	[InstanceEdit:205654] Williams, MG, 2007-07-12 09:20:19
eventOf	[TopLevelPathway:R-DME-5252538] Drosophila signaling pathways - Drosophila melanogaster
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-DME-209442] Formation of the trans-membrane 'signalling complex' - Drosophila melanogaster [Pathway:R-DME-209406] Degradation of NF-kappa-B inhibitor, CACT - Drosophila melanogaster [Pathway:R-DME-209400] Transcriptional activtion by phosphorylated DL/DIF dimer - Drosophila melanogaster
isInDisease	false
isInferred	false
lastUpdatedDate	2020-03-16
literatureReference	[LiteratureReference:208077] The host defense of Drosophila melanogaster [LiteratureReference:208069] The road to Toll [LiteratureReference:208305] The immune response of Drosophila melanogaster [LiteratureReference:208193] Antimicrobial defences in Drosophila: the story so far [LiteratureReference:208357] Regulators of the Toll and Imd pathways in the Drosophila innate immune response [LiteratureReference:208189] The immune response of Drosophila [LiteratureReference:208309] Pathogen recognition and signalling in the Drosophila innate immune response [LiteratureReference:208258] Structure and function of toll receptors and their ligands [LiteratureReference:214930] The Drosophila systemic immune response: sensing and signalling during bacterial and fungal infections [LiteratureReference:214883] The Toll and Imd pathways are the major regulators of the immune response in Drosophila [LiteratureReference:214927] A conserved signaling pathway: the Drosophila toll-dorsal pathway [LiteratureReference:214898] Drosophila MyD88 is required for the response to fungal and Gram-positive bacterial infections [LiteratureReference:214942] Thicker than blood: conserved mechanisms in Drosophila and vertebrate hematopoiesis [LiteratureReference:214935] Blood cells of Drosophila: cell lineages and role in host defence [LiteratureReference:214908] The Drosophila toll gene functions zygotically and is necessary for proper motoneuron and muscle development [LiteratureReference:214909] Autoproteolysis and feedback in a protease cascade directing Drosophila dorsal-ventral cell fate [LiteratureReference:214934] Activation of a protease cascade involved in patterning the Drosophila embryo [LiteratureReference:214867] Weckle is a zinc finger adaptor of the toll pathway in dorsoventral patterning of the Drosophila embryo
maxDepth	4
modified	[InstanceEdit:9847082] Weiser, Joel, 2023-10-12
name	Toll pathway
releaseDate	2009-03-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:386956] Silverman, N, Lemaitre, B, 2008-06-20 10:21:55
schemaClass	Pathway
species	[Species:56210] Drosophila melanogaster
stId	R-DME-209449
summation	[Summation:206495] In Drosophila, the Toll pathway establishes the embryonic do...
updateTrackers	[UpdateTracker:9779670] Update Tracker - [Pathway:209449] Toll pathway - v65:[updateContainedPathway] [UpdateTracker:9777347] Update Tracker - [Pathway:209449] Toll pathway - v72:[updateContainedPathway]

Referrals

(updatedInstance)	[UpdateTracker:9779670] Update Tracker - [Pathway:209449] Toll pathway - v65:[updateContainedPathway] [UpdateTracker:9777347] Update Tracker - [Pathway:209449] Toll pathway - v72:[updateContainedPathway]
(hasEvent)	[TopLevelPathway:R-DME-5252538] Drosophila signaling pathways

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