Reactome | Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA

Schema > Reaction > Entries

Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA Show undefined attributes

catalystActivity	[CatalystActivity:10849439] 3-hydroxyacyl-CoA dehydratase activity of HSD17B4 dimer [peroxisomal matrix]
category	transition
compartment	[Compartment:17951] peroxisomal matrix
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10869473
displayName	Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA
eventOf	[Pathway:R-DME-2046106] alpha-linolenic acid (ALA) metabolism - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DME-2066780] Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA - Drosophila melanogaster
inferredFrom	[Reaction:R-HSA-2066778] Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA - Homo sapiens
input	[SimpleEntity:R-ALL-2066767] delta2-THA-CoA [peroxisomal matrix] [SimpleEntity:R-ALL-141343] H2O [peroxisomal matrix]
isInDisease	false
isInferred	true
maxDepth	1
name	Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA
output	[SimpleEntity:R-ALL-2066766] 1-3-hydroxy-THA-CoA [peroxisomal matrix]
precedingEvent	[Reaction:R-DME-2066787] Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA - Drosophila melanogaster
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-2066778
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-2046106] alpha-linolenic acid (ALA) metabolism
(precedingEvent)	[Reaction:R-DME-2066780] Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA
(inferredTo)	[Reaction:R-HSA-2066778] Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA

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