Reactome | YWHAE (14-3-3 epsilon) dimer binds phosphorylated WWTR1 (TAZ)

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YWHAE (14-3-3 epsilon) dimer binds phosphorylated WWTR1 (TAZ) Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10868796
displayName	YWHAE (14-3-3 epsilon) dimer binds phosphorylated WWTR1 (TAZ)
eventOf	[Pathway:R-DME-2028269] Signaling by Hippo - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-2028651] YWHAE (14-3-3 epsilon) dimer binds phosphorylated WWTR1 (TAZ) - Homo sapiens
input	[EntityWithAccessionedSequence:R-DME-2028665] phospho-yki [cytosol] [Complex:R-DME-194364] YWHAE dimer [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	YWHAE (14-3-3 epsilon) dimer binds phosphorylated WWTR1 (TAZ)
output	[Complex:R-DME-2028649] p-WWTR1:YWHAE [cytosol]
precedingEvent	[Reaction:R-DME-2028661] Phosphorylation of WWTR1 (TAZ) by LATS2 - Drosophila melanogaster
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-2028651
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-2028269] Signaling by Hippo
(inferredTo)	[Reaction:R-HSA-2028651] YWHAE (14-3-3 epsilon) dimer binds phosphorylated WWTR1 (TAZ)

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