Reactome | Phosphorylation of MOB1A and B by p-STK3 (p-MST2)

Schema > Reaction > Entries

Phosphorylation of MOB1A and B by p-STK3 (p-MST2) Show undefined attributes

catalystActivity	[CatalystActivity:10868755] protein serine/threonine kinase activity of p-STK3:p-SAV1 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10868785
displayName	Phosphorylation of MOB1A and B by p-STK3 (p-MST2)
eventOf	[Pathway:R-DME-2028269] Signaling by Hippo - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DME-2028626] Phosphorylated MOB1A proteins associate with LATS proteins - Drosophila melanogaster
inferredFrom	[Reaction:R-HSA-2028635] Phosphorylation of MOB1A and B by p-STK3 (p-MST2) - Homo sapiens
input	2 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [EntityWithAccessionedSequence:R-DME-2028568] MOB1A [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Phosphorylation of MOB1A and B by p-STK3 (p-MST2)
output	2 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [EntityWithAccessionedSequence:R-DME-2028628] phospho-p-T12,T35-MOB1A [cytosol]
precedingEvent	[Reaction:R-DME-2028591] Phosphorylation of STK3 (MST2) and SAV1 by STK3 - Drosophila melanogaster
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-2028635
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-2028269] Signaling by Hippo
(precedingEvent)	[Reaction:R-DME-2028626] Phosphorylated MOB1A proteins associate with LATS proteins
(inferredTo)	[Reaction:R-HSA-2028635] Phosphorylation of MOB1A and B by p-STK3 (p-MST2)

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