Reactome | Calcineurin activates NFAT

Schema > Pathway > Entries

compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10912488
displayName	Calcineurin activates NFAT
eventOf	[Pathway:R-DME-1168372] Downstream signaling events of B Cell Receptor (BCR) - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DME-2025890] Calcineurin binds NFATC1,2,3 - Drosophila melanogaster [Reaction:R-DME-9690461] FKBP1A binds tacrolimus - Drosophila melanogaster
inferredFrom	[Pathway:R-HSA-2025928] Calcineurin activates NFAT - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Calcineurin activates NFAT
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:56210] Drosophila melanogaster
stId	R-DME-2025928
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DME-1168372] Downstream signaling events of B Cell Receptor (BCR)
(inferredTo)	[Pathway:R-HSA-2025928] Calcineurin activates NFAT

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