Reactome | Nuclear Events (kinase and transcription factor activation)

Schema > Pathway > Entries

created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10911596
displayName	Nuclear Events (kinase and transcription factor activation)
eventOf	[Pathway:R-DME-187037] Signaling by NTRK1 (TRKA) - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Pathway:R-DME-198753] ERK/MAPK targets - Drosophila melanogaster [Pathway:R-DME-199920] CREB phosphorylation - Drosophila melanogaster [Pathway:R-DME-9031628] NGF-stimulated transcription - Drosophila melanogaster
inferredFrom	[Pathway:R-HSA-198725] Nuclear Events (kinase and transcription factor activation) - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	4
name	Nuclear Events (kinase and transcription factor activation)
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:56210] Drosophila melanogaster
stId	R-DME-198725
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DME-187037] Signaling by NTRK1 (TRKA)
(inferredTo)	[Pathway:R-HSA-198725] Nuclear Events (kinase and transcription factor activation)

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