Reactome | GAP binds to PDGF-beta receptors only

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GAP binds to PDGF-beta receptors only Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10841183
displayName	GAP binds to PDGF-beta receptors only
eventOf	[Pathway:R-DME-186763] Downstream signal transduction - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-186798] GAP binds to PDGF-beta receptors only - Homo sapiens
input	[Complex:R-DME-389074] Phospho PDGF beta receptor: PDGF chain B homodimer [plasma membrane] [EntityWithAccessionedSequence:R-DME-186833] vap [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	GAP binds to PDGF-beta receptors only
output	[Complex:R-DME-186830] Phospho-beta receptor homodimer:GAP [plasma membrane]
precedingEvent	[Reaction:R-DME-186786] Autophosphorylation of PDGF beta receptors - Drosophila melanogaster
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-186798
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-186763] Downstream signal transduction
(inferredTo)	[Reaction:R-HSA-186798] GAP binds to PDGF-beta receptors only

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