Reactome | GRB2:GAB1:PIK3R1 [cytosol]

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GRB2:GAB1:PIK3R1 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-DME-5654333] Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] - Drosophila melanogaster
consumedByEvent	[Reaction:R-DME-5654667] Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 - Drosophila melanogaster [Reaction:R-DME-5654659] Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 - Drosophila melanogaster [Reaction:R-DME-5654620] Activated FGFR2:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 - Drosophila melanogaster [Reaction:R-DME-5654637] Activated FGFR3:p-FRS2 binds GRB2:GAB1:PIK3R1 - Drosophila melanogaster [Reaction:R-DME-5654641] Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 - Drosophila melanogaster [Reaction:R-DME-5654612] Activated FGFR2:p-FRS2 binds GRB2:GAB1:PIK3R1 - Drosophila melanogaster [Reaction:R-DME-5654594] Activated FGFR1:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 - Drosophila melanogaster [Reaction:R-DME-5654592] Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 - Drosophila melanogaster
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10840787
displayName	GRB2:GAB1:PIK3R1 [cytosol]
hasComponent	[Complex:R-DME-179849] GRB2:GAB1 [cytosol] [EntityWithAccessionedSequence:R-DME-74789] Pi3K21B [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-179864] GRB2:GAB1:PIK3R1 [cytosol] - Homo sapiens
maxDepth	3
name	GRB2:GAB1:PIK3R1
producedByEvent	[Reaction:R-DME-177931] Binding of PIK3 regulatory alpha subunit to GRB2:GAB1 - Drosophila melanogaster
schemaClass	Complex
species	[Species:56210] Drosophila melanogaster
stId	R-DME-179864
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(input)	[Reaction:R-DME-5654667] Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 [Reaction:R-DME-5654594] Activated FGFR1:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 [Reaction:R-DME-5654659] Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 [Reaction:R-DME-5654592] Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 [Reaction:R-DME-5654620] Activated FGFR2:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 [Reaction:R-DME-5654637] Activated FGFR3:p-FRS2 binds GRB2:GAB1:PIK3R1 [Reaction:R-DME-5654641] Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 [Reaction:R-DME-5654612] Activated FGFR2:p-FRS2 binds GRB2:GAB1:PIK3R1
(hasComponent)	[Complex:R-DME-5654333] Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] [Complex:R-DME-5654191] Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] [Complex:R-DME-5654185] Activated FGFR:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] [Complex:R-DME-5654189] Activated FGFR2:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] [Complex:R-DME-5654186] Activated FGFR1:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] [Complex:R-DME-5654194] Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] [Complex:R-DME-5654203] Activated FGFR3:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] [Complex:R-DME-5654199] Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane]
(output)	[Reaction:R-DME-177931] Binding of PIK3 regulatory alpha subunit to GRB2:GAB1
(inferredTo)	[Complex:R-HSA-179864] GRB2:GAB1:PIK3R1 [cytosol]

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