Reactome | SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen

Schema > Reaction > Entries

SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen Show undefined attributes

catalystActivity	[CatalystActivity:10840356] UDP-glucuronate transmembrane transporter activity of SLC35D1 hexamer [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10840358
displayName	SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen
eventOf	[Pathway:R-DME-173599] Formation of the active cofactor, UDP-glucuronate - Drosophila melanogaster [Pathway:R-DME-727802] Transport of nucleotide sugars - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-174368] SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen - Homo sapiens
input	[SimpleEntity:R-ALL-158601] UDP-GlcA [cytosol] [SimpleEntity:R-ALL-162756] UDP-GlcNAc [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen
output	[SimpleEntity:R-ALL-174384] UDP-GlcA [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-3499326] UDP-GlcNAc [endoplasmic reticulum lumen]
precedingEvent	[Reaction:R-DME-173597] UDP-glucose is oxidised to UDP-glucuronate - Drosophila melanogaster
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-174368
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-173599] Formation of the active cofactor, UDP-glucuronate [Pathway:R-DME-727802] Transport of nucleotide sugars
(inferredTo)	[Reaction:R-HSA-174368] SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen

Cite Us!