Reactome | Dissociation of Cdc20 from APC/C complex

Schema > Reaction > Entries

Dissociation of Cdc20 from APC/C complex Show undefined attributes

category	dissociation
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10840316
displayName	Dissociation of Cdc20 from APC/C complex
eventOf	[Pathway:R-DME-176407] Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DME-174070] Association of Cdh1 with the APC/C - Drosophila melanogaster
inferredFrom	[Reaction:R-HSA-174224] Dissociation of Cdc20 from APC/C complex - Homo sapiens
input	[Complex:R-DME-174081] CDC20:p-APC/C [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Dissociation of Cdc20 from APC/C complex
output	[EntityWithAccessionedSequence:R-DME-141412] fzy [cytosol] [Complex:R-DME-174191] phosphorylated anaphase promoting complex (APC/C) [cytosol]
precedingEvent	[BlackBoxEvent:R-DME-174157] Degradation of multiubiquitinated Cyclin B - Drosophila melanogaster [BlackBoxEvent:R-DME-174202] Degradation of multiubiquitinated Securin - Drosophila melanogaster [Reaction:R-DME-174238] Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 - Drosophila melanogaster
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-174224
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-176407] Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
(precedingEvent)	[Reaction:R-DME-174070] Association of Cdh1 with the APC/C
(inferredTo)	[Reaction:R-HSA-174224] Dissociation of Cdc20 from APC/C complex