Reactome | Dissociation of phosphorylated 4EBP1 from eIF4E

Schema > Reaction > Entries

Dissociation of phosphorylated 4EBP1 from eIF4E Show undefined attributes

category	dissociation
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10839310
displayName	Dissociation of phosphorylated 4EBP1 from eIF4E
eventOf	[Pathway:R-DME-166208] mTORC1-mediated signalling - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-165708] Dissociation of phosphorylated 4EBP1 from eIF4E - Homo sapiens
input	[Complex:R-DME-165697] eIF4E:4E-BP1-P [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Dissociation of phosphorylated 4EBP1 from eIF4E
output	[EntityWithAccessionedSequence:R-DME-72578] EIF4E [cytosol] [EntityWithAccessionedSequence:R-DME-165685] phospho-Thor [cytosol]
precedingEvent	[Reaction:R-DME-165692] Phosphorylation of 4E-BP1 by activated mTORC1 - Drosophila melanogaster
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-165708
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-166208] mTORC1-mediated signalling
(inferredTo)	[Reaction:R-HSA-165708] Dissociation of phosphorylated 4EBP1 from eIF4E

Cite Us!