Reactome | PKA activation in glucagon signalling

Schema > Pathway > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10911052
displayName	PKA activation in glucagon signalling
eventOf	[Pathway:R-DME-163359] Glucagon signaling in metabolic regulation - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:528562] cellular response to glucagon stimulus
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DME-111925] cAMP induces dissociation of inactive PKA tetramers - Drosophila melanogaster
inferredFrom	[Pathway:R-HSA-164378] PKA activation in glucagon signalling - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	PKA activation in glucagon signalling
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:56210] Drosophila melanogaster
stId	R-DME-164378
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DME-163359] Glucagon signaling in metabolic regulation
(inferredTo)	[Pathway:R-HSA-164378] PKA activation in glucagon signalling

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