Reactome | MT-MMPs are sorted to the plasma membrane

Schema > BlackBoxEvent > Entries

category	omitted
compartment	[Compartment:17963] Golgi lumen [Compartment:876] plasma membrane
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10863612
displayName	MT-MMPs are sorted to the plasma membrane
eventOf	[Pathway:R-DME-1592389] Activation of Matrix Metalloproteinases - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-1605825] MT-MMPs are sorted to the plasma membrane - Homo sapiens
input	[CandidateSet:R-DME-1604727] MT-MMPs [Golgi lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	MT-MMPs are sorted to the plasma membrane
output	[CandidateSet:R-DME-1605821] MT-MMPs [plasma membrane]
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:56210] Drosophila melanogaster
stId	R-DME-1605825
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DME-1592389] Activation of Matrix Metalloproteinases
(inferredTo)	[BlackBoxEvent:R-HSA-1605825] MT-MMPs are sorted to the plasma membrane

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