Reactome | Elevation of cytosolic Ca2+ levels

Schema > Pathway > Entries

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10911114
displayName	Elevation of cytosolic Ca2+ levels
eventOf	[Pathway:R-DME-418360] Platelet calcium homeostasis - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DME-139854] IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol - Drosophila melanogaster
inferredFrom	[Pathway:R-HSA-139853] Elevation of cytosolic Ca2+ levels - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Elevation of cytosolic Ca2+ levels
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:56210] Drosophila melanogaster
stId	R-DME-139853
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DME-418360] Platelet calcium homeostasis
(inferredTo)	[Pathway:R-HSA-139853] Elevation of cytosolic Ca2+ levels

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