Reactome | RBL2:E2F4,E2F5:TFDP1,TFDP2 [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-DME-1363300] RBL2:E2F4/5:DP1/2:Cyclin E/A:CDK2 [nucleoplasm] - Drosophila melanogaster [Complex:R-DME-1227666] HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2 [nucleoplasm] - Drosophila melanogaster
consumedByEvent	[Reaction:R-DME-1363303] p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2 - Drosophila melanogaster [Reaction:R-DME-1226094] Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex - Drosophila melanogaster [Reaction:R-DME-1362261] p130 (RBL2) associates with MuvB to form DREAM complex - Drosophila melanogaster [Reaction:R-DME-1227670] Recruitment of HDAC1 by p130 (RBL2) - Drosophila melanogaster
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10860835
displayName	RBL2:E2F4,E2F5:TFDP1,TFDP2 [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-DME-68652] Dp [nucleoplasm] [DefinedSet:R-DME-1226069] E2F4,E2F5 [nucleoplasm] [EntityWithAccessionedSequence:R-DME-389102] Rbf [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-1226089] RBL2:E2F4,E2F5:TFDP1,TFDP2 [nucleoplasm] - Homo sapiens
maxDepth	4
name	RBL2:E2F4,E2F5:TFDP1,TFDP2
schemaClass	Complex
species	[Species:56210] Drosophila melanogaster
stId	R-DME-1226089
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-DME-1363303] p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2 [Reaction:R-DME-1227670] Recruitment of HDAC1 by p130 (RBL2) [Reaction:R-DME-1226094] Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex [Reaction:R-DME-1362261] p130 (RBL2) associates with MuvB to form DREAM complex
(hasComponent)	[Complex:R-DME-1363300] RBL2:E2F4/5:DP1/2:Cyclin E/A:CDK2 [nucleoplasm] [Complex:R-DME-1227666] HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2 [nucleoplasm] [Complex:R-DME-1362264] DREAM complex [nucleoplasm]
(inferredTo)	[Complex:R-HSA-1226089] RBL2:E2F4,E2F5:TFDP1,TFDP2 [nucleoplasm]

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