Reactome | PKR inhibitors bind PKR

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11047295
displayName	PKR inhibitors bind PKR
eventOf	[Pathway:R-DDI-9833482] PKR-mediated signaling - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9836702] PKR inhibitors bind PKR - Homo sapiens
input	[DefinedSet:R-DDI-168699-3] Homologues of EIF2AK2 [cytosol] [DefinedSet:R-ALL-9836704] PKR inhibitors [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	PKR inhibitors bind PKR
output	[Complex:R-DDI-9836700] EIF2AK2:PKR inhibitors [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-9836702
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DDI-9833482] PKR-mediated signaling
(inferredTo)	[Reaction:R-HSA-9836702] PKR inhibitors bind PKR

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